| Speelronde 21 en 22 | | |
| 21 mei 2022 | Ronde 21 | Ronde 22 |
| Valken | Chelsea – Manchester City | Chelsea – Atletico Madrid |
| | Juventus – Villarreal | Juventus – Manchester City |
| | Bayern Munchen – Porto | Bayern Munchen – Monaco |
| | Celtic – Monaco | Celtic – Internazionale |
| | AC Milan – Internazionale | AC Milan – Galatasary |
| | Atletico Madrid – Galatasary | Villarreal – Porto |
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| Woudia | Real Madrid – Barcelona | Real Madrid – Anderlecht |
| | Borussia Dortmund – Anderlecht | Barcelona – Borussia Dortmund |
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| Speelronde 23 en 24 | | |
| 11 juni 2022 | Ronde 23 | Ronde 24 |
| Valken | Manchester City – AC Milan | Manchester City – Internazionale |
| | Borussia Dortmund – Monaco | Borussia Dortmund – AC Milan |
| | Villarreal – Atletico Madrid | Atletico Madrid – Barcelona |
| | Internazionale – Juventus | Anderlecht – Monaco |
| | Porto – Barcelona | Porto – Juventus |
| | Galatasary – Anderlecht | Galatasary – Villarreal |
| Real Madrid – Chelsea | Real Madrid – Bayern Munchen |
| Baryern Munchen – Celtic | Chelsea – Celtic |
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